Molecular Devices

From cellular images to results in minutes with automated cellular imaging and analysis 

From cellular images to results in minutes with automated cellular imaging and analysis

Date: Wednesday, October, 17, 2018

Time: 8:00 AM PST | 11:00 AM EST | 4:00 PM BST | 5:00 PM CET

Presenters: (Read presenter biographies below form)

Oksana Sirenko | Senior Research Scientist, Molecular Devices

Jeff McMillan | Product Manager, Cellular Imaging, Molecular Devices

Abstract:

There is a great need to automate complex cell-based assays with multi-parametric readouts while maintaining high data quality and precision. We explore the accessibility and utility of a new automated imaging system for biological research and will present several assay models that are useful for both academic and bio-pharma environments.

The ImageXpress™ Pico Automated Cell Imaging System was used to develop several multi-parametric assays utilizing iPSC-derived cardiomyocytes, neurons, and hepatocytes. Multiple readouts include cell viability, apoptosis, mitochondria membrane potential and autophagy for defining mechanisms of toxicity in live or fixed cells.

Additionally, attendees will receive a special promotional offer for the ImageXpress Pico system.

Learning Objectives:

  • Learn about different examples of multi-parametric assays utilizing different stem cell models and automated imaging
  • Enable automatic monitoring of neurite outgrowth, calcium oscillations in cardiomyocytes, cell proliferation, differentiation, compound toxicity and a variety of other cell-based assays
  • Use preconfigured protocols to simplify the setup and shorten the learning curve, so you can get started quickly
  • Generate multiple readouts to better characterize the phenotypic effects of different compound and measure effectiveness of concentrations

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Presenter Biographies

  Oksana Sirenko earned her Ph.D. in Biochemistry from the Biochemistry Research Institute, Academy of Sciences in Ukraine. For over 15 years, she has worked as a Research Scientist in cell-based assay development, drug discovery and drug development in several pharma and biotech companies, including Novartis, Bayer, and Fibrogen. At Molecular Devices she is focused on assay development using high-content imaging systems and other instruments to develop methods for cell-based disease modelling and toxicity research.
     
 

Jeff McMillan, Senior Imaging Product Manager from Molecular Devices, has an extensive product management background with over 20 years of expertise managing life sciences and clinical measurement systems from mass spectrometers and flow cytometers to cellular imaging systems.  He has a Bachelors of Physics from University of California, Berkeley and a Masters of Business Administration from Santa Clara University.