Molecular Devices

Quantitate GPCR activation using automated cell imaging and analysis

GPCRs play an integral role in a wide range of biological pathways and are a crucial target for drug discovery. Many GPCRs are still classified as orphan receptors, which are GPCRs whose interacting ligand has not yet been discovered. To enable a better understanding of ligand-GPCR relationships, automated imaging can be used to generate highly informative and biologically relevant phenotypic data.

  • Screen for ligands to known and orphan GPCRs
  • Apply a predefined image analysis module for quantifying multiple subcellular objects
  • Enable rapid results with simultaneous image acquisition and analysis
 

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