Molecular Devices

Download Poster: Rapid Monoclonality Verification Methods to Boost Cell Line Development

Abstract

Regulations for cell line development are increasingly more stringent. Providing evidence that a cell line is derived from a single cell is a crucial factor in cell line generation.
While monoclonality verification via white light imaging is possible, debris, dust, and air bubbles make it difficult and time consuming to identify single cells which may cause high value
clones to be discarded.

In this poster, we present a fluoscence approach for identifying monoclonal CHO-S cells that enables easier and more conclusive monoclonality verification than the traditional white
light method.

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